Description

Bay 60-7550 is a potent and selective phosphodiesterase 2A (PDE2A) inhibitor, a key compound for modulating cyclic nucleotide signaling pathways in biological research. Its high selectivity makes it an invaluable pharmacological tool for investigating cognitive function, neuroprotection, and cardiovascular regulation. This product is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on neuroscience, cardiology, and drug discovery programs.

Application

• Neuroscience Research: Used as a selective tool compound to study the role of PDE2A in memory, learning, and synaptic plasticity.
• Drug Discovery & Development: Serves as a reference standard and lead compound for developing novel therapeutics targeting cognitive disorders.
• Cardiovascular Research: Employed in studies exploring PDE2A's function in heart tissue and vascular tone regulation.
• Biochemical Assays: Acts as a critical inhibitor in enzymatic assays to characterize PDE2A activity and screen for new inhibitors.
• Academic & Institutional Research: Provides a reliable research chemical for fundamental studies on cyclic nucleotide signaling in various disease models.
• Preclinical Studies: Utilized in animal models to evaluate the therapeutic potential of PDE2A inhibition for conditions like Alzheimer's disease and schizophrenia.

Basic Information

Product Name	Bay 60-7550
CAS No.	439083-90-6
Molecular Formula	C₂₀H₂₅N₅O₂
Molecular Weight	367.45 g/mol
Synonyms	BAY 60-7550; 1-(4,6-Dimethylpyrimidin-2-yl)-4-(4-methoxyphenyl)piperazine; PDE2 Inhibitor III; PDE2A Inhibitor; 4-(4-Methoxyphenyl)-1-(4,6-dimethyl-2-pyrimidinyl)piperazine
EINECS	Contact for details

Quality Control

Our Bay 60-7550 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.