Description

5-Nitro-2-(Trifluoromethyl)Pyridin-4-Ol is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both nitro and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for developing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	5-Nitro-2-(Trifluoromethyl)Pyridin-4-Ol
CAS No.	438554-44-0
Molecular Formula	C6H3F3N2O3
Molecular Weight	208.10 g/mol
Synonyms	4-Hydroxy-5-nitro-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-5-nitropyridin-4-ol; 5-Nitro-2-trifluoromethylpyridin-4-ol; 4-Pyridinol, 5-nitro-2-(trifluoromethyl)-; 438554-44-0; 5-Nitro-2-(trifluoromethyl)-4-pyridinol
EINECS	Contact for details

Quality Control

Every batch of 5-Nitro-2-(Trifluoromethyl)Pyridin-4-Ol is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.