Description

4-Cyano-3,5-Difluoro Benzaldehyde is a versatile aromatic aldehyde building block characterized by its strategically placed cyano and fluorine substituents. This compound is highly valued for its role as a key intermediate in the synthesis of advanced pharmaceutical compounds and functional materials. It is primarily sought after by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the difluoro and cyano groups contribute to biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for high-performance liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and production of organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research to explore new chemical entities and properties.

Basic Information

Product Name	4-Cyano-3,5-Difluoro Benzaldehyde
CAS No.	433939-88-9
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	3,5-Difluoro-4-formylbenzonitrile; 3,5-Difluoro-4-cyanobenzaldehyde; Benzaldehyde, 4-cyano-3,5-difluoro-; 4-Formyl-2,6-difluorobenzonitrile; 2,6-Difluoro-4-cyanobenzaldehyde; 4-Cyano-2,6-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Cyano-3,5-Difluoro Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.