Description

n-(3,4-Dimethoxyphenethyl)-2-((4-Oxo-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetamide CAS NO 433699-35-5 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams working on kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the synthesis of potent and selective kinase inhibitors due to its fused thienopyrimidine structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecular architectures in academic and industrial laboratories.
• Biochemical Tool Compound: Potential use as a reference standard or probe in biochemical assays to study specific enzyme pathways and cellular mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-(3,4-Dimethoxyphenethyl)-2-((4-Oxo-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetamide
CAS No.	433699-35-5
Molecular Formula	C23H25N3O4S2
Molecular Weight	471.59 g/mol
Synonyms	2-(((4-Oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide; N-(3,4-Dimethoxyphenethyl)-2-((4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide; 433699-35-5; Cyclopenta[4,5]thieno[2,3-d]pyrimidine acetamide derivative; Thienopyrimidine acetamide intermediate; CAS 433699-35-5
EINECS	Contact for details

Quality Control

Our n-(3,4-Dimethoxyphenethyl)-2-((4-Oxo-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.