Description

2,2,2-Trifluoro-n-(4-{[(4-Iodophenyl)Amino]Sulfonyl}Phenyl)Acetamide is a specialized organic compound featuring a trifluoroacetamide core linked to a sulfonamide-aniline scaffold with an iodine substituent. This unique molecular architecture makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme receptors where the iodine and sulfonamide groups are critical for activity.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, where its aromatic and halogenated components influence material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of the reactive iodine atom.
• Bioconjugation & Probe Development: Utilized in creating chemical probes and diagnostic agents for biochemical research.

Basic Information

Item	Detail
Product Name	2,2,2-Trifluoro-n-(4-{[(4-Iodophenyl)Amino]Sulfonyl}Phenyl)Acetamide
CAS No.	433310-47-5
Molecular Formula	C14H10F3IN2O3S
Molecular Weight	494.20 g/mol
Synonyms	N-[4-[(4-Iodoanilino)sulfonyl]phenyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[4-[[(4-iodophenyl)amino]sulfonyl]phenyl]acetamide; 4'-[(4-Iodophenyl)sulfamoyl]trifluoroacetanilide; TFIA; Trifluoroacetamide Sulfonamide Iodobenzene Derivative
EINECS	Contact for details

Quality Control

Our production of 2,2,2-Trifluoro-n-(4-{[(4-Iodophenyl)Amino]Sulfonyl}Phenyl)Acetamide adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.