Description

6H-Purin-6-One, 2-Amino-1,8-Dihydro-8-Hydroxy-, Radical Ion(1-) (9Ci) is a specialized purine derivative of significant interest in advanced chemical synthesis and research. This compound serves as a critical intermediate or precursor in the development of novel pharmaceutical agents and biochemical probes. It is primarily sought by research institutions and industrial R&D departments focused on nucleotide chemistry, oncology research, and the synthesis of modified nucleobases.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel purine-based drug candidates, particularly for targeted therapies.
• Biochemical Research: Used as a precursor or standard in studies involving radical chemistry, nucleotide metabolism, and enzyme inhibition assays.
• Nucleic Acid Chemistry: Employed in the development of modified nucleosides and nucleotides for diagnostic or therapeutic applications.
• Oncology Research: Investigated for its potential role in the design of compounds that interact with DNA repair pathways or cell cycle regulation.
• Chemical Synthesis: Serves as a versatile intermediate for introducing the 2-amino-8-hydroxypurine scaffold into more complex molecular architectures.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6H-Purin-6-One, 2-Amino-1,8-Dihydro-8-Hydroxy-, Radical Ion(1-) (9Ci)
CAS No.	433302-89-7
Molecular Formula	C5H4N5O-
Molecular Weight	150.12 g/mol (for neutral form C5H5N5O)
Synonyms	2-Amino-8-hydroxy-9H-purin-6(1H)-one radical anion; 2-Amino-8-hydroxypurine-6-one radical ion(1-); 8-Hydroxy-2-aminopurine-6-one radical anion; 2-Amino-1,8-dihydro-8-hydroxypurin-6-one radical anion; 2-Amino-8-oxo-7,8-dihydro-9H-purin-6-ol radical anion; Radical anion of 2-amino-8-hydroxypurine-6-one; 9Ci Index Name derivative.
EINECS	Contact for details

Quality Control

Our production of 6H-Purin-6-One, 2-Amino-1,8-Dihydro-8-Hydroxy-, Radical Ion(1-) (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at controlled room temperature (15-25°C) in a dry environment. This compound may be sensitive to oxidation and moisture; handle under an inert atmosphere when appropriate for extended use.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.