Description

3-(4-Trifluoromethyl)Phenylpyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethylphenyl group, is engineered to impart unique electronic and steric properties to target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as charge-transport layers in OLEDs and other optoelectronic devices.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorophores for diagnostic and imaging applications.

Basic Information

Product Name	3-(4-Trifluoromethyl)Phenylpyridine
CAS No.	426823-25-8
Molecular Formula	C12H8F3N
Molecular Weight	223.20 g/mol
Synonyms	3-[4-(Trifluoromethyl)phenyl]pyridine; 4-(3-Pyridinyl)benzotrifluoride; 3-(4-Trifluoromethylphenyl)pyridine; 3-(p-Trifluoromethylphenyl)pyridine; 3-(4-(Trifluoromethyl)phenyl)pyridine; Pyridine, 3-[4-(trifluoromethyl)phenyl]-; 426823-25-8
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl)Phenylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.