Description

2-Propenal, 3-(3,5-Difluorophenyl)-, (2E)- is a specialized fluorinated organic building block with the CAS number 405937-99-7. This compound is valued for its unique α,β-unsaturated carbonyl structure, which provides a reactive handle for constructing more complex molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in advanced synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents, leveraging the difluorophenyl moiety for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers or advanced organic materials with tailored electronic or surface properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and ligands for studying enzyme mechanisms or receptor interactions.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Conjugate Addition Substrate: Its α,β-unsaturated system is ideal for Michael addition reactions, a fundamental transformation in organic synthesis.

Basic Information

Product Name	2-Propenal, 3-(3,5-Difluorophenyl)-, (2E)-
CAS No.	405937-99-7
Molecular Formula	C9H5F2O
Molecular Weight	167.13 g/mol
Synonyms	(2E)-3-(3,5-Difluorophenyl)prop-2-enal; 3-(3,5-Difluorophenyl)-2-propenal; (E)-3-(3,5-Difluorophenyl)acrylaldehyde; trans-3-(3,5-Difluorocinnamaldehyde); 3,5-Difluorocinnamaldehyde; (E)-3-(3,5-Difluorophenyl)acrylic aldehyde; 3-(3,5-Difluorophenyl)acrylaldehyde
EINECS	Contact for details

Quality Control

Our 2-Propenal, 3-(3,5-Difluorophenyl)-, (2E)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.