Description

2-Fluoro-6-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the sulfonyl chloride group combined with the electron-withdrawing properties of the fluorine and trifluoromethyl substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require a reliable, high-quality intermediate for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that leverage the stability and bioactivity of the fluorinated sulfonamide moiety.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and advanced functional materials.
• Chemical Research & Development: Employed as a versatile reagent for introducing the sulfonyl group into complex molecules, facilitating structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	2-Fluoro-6-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride
CAS No.	405264-04-2
Molecular Formula	C7H3ClF4O2S
Molecular Weight	262.61 g/mol
Synonyms	2-Fluoro-6-(trifluoromethyl)benzenesulfonyl chloride; 2-Fluoro-alpha,alpha,α-trifluoro-o-toluenesulfonyl chloride; 1-(Chlorosulfonyl)-2-fluoro-3-(trifluoromethyl)benzene; o-Fluoro-alpha,alpha,α-trifluorotoluene-2-sulfonyl chloride; 2-Fluoro-6-trifluoromethylbenzenesulfonyl chloride; 405264-04-2; Benzenesulfonyl chloride, 2-fluoro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride is produced and tested under a strict quality management system to ensure high purity and batch-to-batch consistency. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.