Description

Soluble Epoxide Hydrolase Inhibitor, Ncnd - Calbiochem is a potent and selective small molecule inhibitor of the soluble epoxide hydrolase (sEH) enzyme. This compound is a critical research tool for investigating the role of epoxyeicosatrienoic acids (EETs) in inflammatory, cardiovascular, and neurological pathways. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on metabolic disease, pain, and hypertension. The product is supplied under the Calbiochem brand, signifying high standards of quality and reliability for biochemical research.

Application

• Biochemical Research: A key pharmacological tool for studying the sEH enzyme pathway and its physiological effects.
• Drug Discovery & Development: Used in high-throughput screening (HTS) and target validation for novel therapeutics targeting inflammation and pain.
• Academic Studies: Facilitates in vitro and in vivo research into cardiovascular protection, neuroinflammation, and renal function.
• Mechanistic Pharmacology: Helps elucidate the anti-inflammatory and vasodilatory mechanisms mediated by stabilized EETs.
• Biomarker Research: Supports studies on the relationship between sEH activity and disease states.

Basic Information

Product Name	Soluble Epoxide Hydrolase Inhibitor, Ncnd - Calbiochem
CAS No.	402939-18-8
Molecular Formula	C21H21F3N2O3
Molecular Weight	406.40 g/mol
Synonyms	1-(1-Methanesulfonyl-piperidin-4-yl)-3-(4-trifluoromethoxy-phenyl)-urea; Ncnd; sEH Inhibitor Ncnd; sEHI Ncnd; Soluble Epoxide Hydrolase Inhibitor Ncnd; CAS 402939-18-8; Calbiochem sEH Inhibitor
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured and tested to meet the exacting standards required for advanced research. Certificates of Analysis (COA) are provided, detailing purity, identity, and potency. Our quality assurance protocols ensure batch-to-batch consistency and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Biological Activity (sEH Inhibition IC50)	Contact for details
Solubility	DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.