Description

Ac-Leu-Glu-Val-Asp-Aldehyde (Pseudo Acid) is a specialized peptide aldehyde derivative, functioning as a potent and selective protease inhibitor. This compound is critical for biochemical research and pharmaceutical development, particularly in the study of programmed cell death (apoptosis) pathways. It serves as a valuable tool for researchers and manufacturers in the life sciences, biotechnology, and drug discovery sectors who require high-purity biochemical reagents for enzyme inhibition studies.

Application

• Caspase Inhibition Studies: Primarily used as a potent, cell-permeable inhibitor of caspase-3 and related caspases, key enzymes in apoptosis.
• Biochemical Research: A crucial tool compound for investigating protease function, enzyme kinetics, and signal transduction pathways in vitro.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify and characterize novel therapeutic agents targeting apoptotic disorders.
• Cell Biology: Used to modulate apoptosis in cell culture models to study diseases like cancer, neurodegeneration, and autoimmune conditions.
• Peptide Chemistry Reference Standard: Serves as a high-purity reference material for analytical method development and quality control in peptide synthesis.

Basic Information

Product Name	Ac-Leu-Glu-Val-Asp-Aldehyde (Pseudo Acid)
CAS No.	402832-01-3
Molecular Formula	C22H34N4O8
Molecular Weight	482.53 g/mol
Synonyms	Ac-LEVD-CHO; Ac-Leu-Glu-Val-Asp-H; Acetyl-Leu-Glu-Val-Asp-aldehyde; Caspase-3 Inhibitor I; N-Acetyl-Leu-Glu-Val-Asp-al; Apoptosis Inhibitor; N-Acetyl-L-leucyl-L-α-glutamyl-L-valyl-L-α-aspartyl aldehyde
EINECS	Contact for details

Quality Control

Our Ac-Leu-Glu-Val-Asp-Aldehyde (Pseudo Acid) is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.