Description

n-(3,5-Dichloro-2-Methoxyphenyl)-4-Methoxy-3-(1-Piperazinyl)-Benzenesulfonamide Hydrochloride is a high-purity, synthetically derived chemical intermediate of significant importance in advanced pharmaceutical research and development. This compound is valued for its specific structural features, including the piperazinyl and sulfonamide moieties, which are key pharmacophores in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antimicrobial targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable piperazine and sulfonamide functional groups.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of assays for studying enzyme inhibition or receptor binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial drug candidates.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	n-(3,5-Dichloro-2-Methoxyphenyl)-4-Methoxy-3-(1-Piperazinyl)-Benzenesulfonamide Hydrochloride
CAS No.	402713-81-9
Molecular Formula	C19H22Cl2N4O4S • HCl
Molecular Weight	502.83 g/mol (for hydrochloride salt)
Synonyms	4-Methoxy-3-(1-piperazinyl)-N-(3,5-dichloro-2-methoxyphenyl)benzenesulfonamide hydrochloride; 3,5-Dichloro-2-methoxy-N-[4-methoxy-3-(1-piperazinyl)phenyl]sulfonyl]aniline hydrochloride; Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-, hydrochloride; CAS 402713-81-9; 402713-81-9; 3-(Piperazin-1-yl)-4-methoxy-N-(3,5-dichloro-2-methoxyphenyl)benzenesulfonamide hydrochloride.
EINECS	Contact for details

Quality Control

Our n-(3,5-Dichloro-2-Methoxyphenyl)-4-Methoxy-3-(1-Piperazinyl)-Benzenesulfonamide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.