Description

2-[(3-Trifluoromethyl)Phenyl]-4,6-Dimethoxypyrimidine is a high-purity, functionalized pyrimidine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique trifluoromethylphenyl moiety, which imparts desirable properties like enhanced metabolic stability and lipophilicity to final compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients. The compound is supplied with a CAS number of 402497-49-8.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a precursor for organic electronic materials and liquid crystals due to its aromatic and electron-deficient structure.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, complex heterocyclic architectures.

Basic Information

Item	Details
Product Name	2-[(3-Trifluoromethyl)Phenyl]-4,6-Dimethoxypyrimidine
CAS No.	402497-49-8
Molecular Formula	C13H11F3N2O2
Molecular Weight	284.24 g/mol
Synonyms	2-(3-(Trifluoromethyl)phenyl)-4,6-dimethoxypyrimidine; 4,6-Dimethoxy-2-[3-(trifluoromethyl)phenyl]pyrimidine; α,α,α-Trifluoro-m-tolyl-4,6-dimethoxypyrimidine; 2-(3-Trifluoromethylphenyl)-4,6-dimethoxypyrimidine; 2-(m-Trifluoromethylphenyl)-4,6-dimethoxypyrimidine; 402497-49-8; 2-(3-(Trifluoromethyl)phenyl)-4,6-dimethoxy-pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-[(3-Trifluoromethyl)Phenyl]-4,6-Dimethoxypyrimidine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment supports compliance in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.