Description

2,6-Difluoropyridine-4-Boronic Acid is a high-value organoboron building block, specifically a pyridine boronic acid derivative. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,6-Difluoropyridine-4-Boronic Acid
CAS No.	401816-16-8
Molecular Formula	C5H4BF2NO2
Molecular Weight	158.90 g/mol
Synonyms	(4-Borono-2,6-difluoropyridine); 2,6-Difluoropyridine-4-boronic acid; 2,6-Difluoro-4-pyridineboronic acid; 4-Borono-2,6-difluoropyridine; 2,6-Difluoro-4-pyridinylboronic acid; (2,6-Difluoropyridin-4-yl)boronic acid; B-(2,6-Difluoropyridin-4-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoropyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.