Description

3'-Fluorobiphenyl-3-Carbaldehyde is a versatile fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique biphenyl core with a strategically placed fluorine atom and formyl group makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers for electronic and optoelectronic applications.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for developing fluorescent markers and dyes used in bio-imaging and analytical chemistry.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.

Basic Information

Product Name	3'-Fluorobiphenyl-3-Carbaldehyde
CAS No.	400750-09-6
Molecular Formula	C13H9FO
Molecular Weight	200.21 g/mol
Synonyms	3-Formyl-3'-fluorobiphenyl; [1,1'-Biphenyl]-3-carboxaldehyde, 3'-fluoro-; 3'-Fluoro-[1,1'-biphenyl]-3-carbaldehyde; 3'-Fluoro-3-biphenylcarboxaldehyde; 3-(3-Fluorophenyl)benzaldehyde; 3'-Fluorobiphenyl-3-aldehyde
EINECS	Contact for details

Quality Control

Every batch of 3'-Fluorobiphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.