Description

Prostaglandin D2 Methyl Ester is a chemically modified, stabilized form of the important lipid mediator Prostaglandin D2 (PGD2). This methyl ester derivative is crucial for research and development, offering enhanced stability for handling and storage compared to the free acid form. It serves as a key biochemical tool and synthetic intermediate for scientists in the pharmaceutical and life science sectors, particularly those investigating inflammation, allergy, sleep regulation, and oncology pathways.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of DP1 and CRTH2 receptor signaling pathways.
• Pharmaceutical Development: Acts as a critical intermediate in the synthesis of novel prostaglandin analogs and drug candidates targeting allergic and inflammatory diseases.
• Cell Biology Studies: Employed to investigate the role of PGD2 in processes such as apoptosis, glial cell function, and neuromodulation.
• Analytical Standard: Serves as a high-purity standard for HPLC, LC-MS, and GC-MS methods in analytical laboratories for quantification and method validation.
• Metabolite Synthesis: Utilized as a precursor for the synthesis of downstream PGD2 metabolites like 15-deoxy-δ¹²,¹⁴-PGJ₂ for specialized research applications.

Basic Information

Product Name	Prostaglandin D2 Methyl Ester
CAS No.	49852-81-5
Molecular Formula	C₂₂H₃₆O₅
Molecular Weight	380.52 g/mol
Synonyms	PGD2 Methyl Ester; Methyl (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oate; (15S)-9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic Acid Methyl Ester; 9α,15S-Dihydroxy-11-oxoprosta-5,13-dien-1-oic Acid Methyl Ester; Methyl 9α,15-dihydroxy-11-oxoprosta-5,13-dien-1-oate
EINECS	Contact for details

Quality Control

Our Prostaglandin D2 Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.