Description

4-(Aminosulfonyl)Benzenesulfonyl Chloride is a high-purity, bifunctional sulfonyl chloride derivative of significant synthetic utility. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the introduction of both sulfonamide and sulfonyl chloride functional groups. It is primarily sought after by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that utilize sulfonylurea or sulfonamide chemistries.
• Dyestuff and Pigment Manufacturing: Acts as a reactive intermediate for producing sulfonated dyes and pigments with enhanced solubility and color fastness.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer backbones, altering properties like hydrophilicity, ionic conductivity, or thermal stability.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science for constructing complex molecules and exploring new synthetic pathways.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal complexes or functionalizing solid supports for catalysis.

Basic Information

Product Name	4-(Aminosulfonyl)Benzenesulfonyl Chloride
CAS No.	46249-41-6
Molecular Formula	C6H6ClNO4S2
Molecular Weight	255.70 g/mol
Synonyms	4-Sulfamoylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-(aminosulfonyl)-; p-Sulfamoylbenzenesulfonyl chloride; 4-Carbamoylbenzenesulfonyl chloride (common misnomer); 1,4-Benzenedisulfonyl chloride monoamide; 4-Aminosulfonylbenzene-1-sulfonyl chloride; 4-(Chlorosulfonyl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Every batch of 4-(Aminosulfonyl)Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA), including results for assay, purity (by HPLC), and identification, is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under a dry, inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.