Description

4-Pyridinol, 2,6-Bis(Trifluoromethyl)- CAS NO 43150-55-6 is a highly fluorinated pyridine derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups, makes it a critical intermediate for developing compounds with tailored electronic and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorinated motifs for enhanced bioactivity, stability, and performance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Acts as a sophisticated ligand precursor for transition metal catalysts used in cross-coupling and other fine chemical reactions.
• Material Science Research: Employed in the creation of fluorinated polymers, liquid crystals, and electronic materials for specialized applications.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and discovery chemistry programs exploring structure-activity relationships.

Basic Information

Product Name	4-Pyridinol, 2,6-Bis(Trifluoromethyl)-
CAS No.	43150-55-6
Molecular Formula	C7H3F6NO
Molecular Weight	231.10 g/mol
Synonyms	2,6-Bis(trifluoromethyl)pyridin-4-ol; 2,6-Bis(trifluoromethyl)-4-pyridinol; 4-Hydroxy-2,6-bis(trifluoromethyl)pyridine; 2,6-Bis(trifluoromethyl)-4-hydroxypyridine; 4-Pyridinol, 2,6-bis(trifluoromethyl)-; 2,6-Di(trifluoromethyl)-4-pyridone (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinol, 2,6-Bis(Trifluoromethyl)- is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.