Description

Clomiphene Citrate CAS NO 43054-45-1 is a non-steroidal selective estrogen receptor modulator (SERM) of the triphenylethylene class. This compound is of significant commercial and research interest due to its ability to stimulate ovulation by blocking estrogen receptors in the hypothalamus. It is a critical active pharmaceutical ingredient (API) primarily required by the pharmaceutical industry for fertility treatments and is also utilized in biochemical research and reference standard production.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of ovulatory dysfunction and anovulatory infertility.
• Fertility Treatment: Used in clinical settings to induce ovulation in women with polycystic ovary syndrome (PCOS) or other fertility challenges.
• Research Chemical: Employed in biochemical and pharmacological research to study estrogen receptor modulation, endocrine pathways, and reproductive biology.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical manufacturing and regulatory compliance.
• Veterinary Medicine: Potential application in veterinary reproductive therapy for certain animal species.

Basic Information

Product Name	Clomiphene Citrate
CAS No.	43054-45-1
Molecular Formula	C32H36ClNO8 • C6H8O7
Molecular Weight	598.09 g/mol (Free base: 405.96 g/mol)
Synonyms	Clomifene Citrate; Clomid® (Brand Name); 2-[4-(2-Chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine Citrate; Zu/Zu Clomiphene; NSC-35770; MRL-41; Enclomiphene Citrate and Zuclomiphene Citrate Mixture; Ethamoxytriphetol Citrate
EINECS	256-056-0

Quality Control

Our Clomiphene Citrate is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Enantiomeric Ratio (Zuclomiphene/Enclomiphene)	Approximately 62:38 (or as per customer requirement)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.