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9Alpha-11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Oic Acid, 1-Glyceryl Ester CAS NO 43042-79-1
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CAS No.:43042-79-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9Alpha-11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Oic Acid, 1-Glyceryl Ester is a high-purity, chemically defined prostaglandin derivative, specifically a glyceryl ester of a trihydroxy prostanoid acid. This compound is of significant value as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on prostaglandin-based therapeutics, metabolic pathway studies, and the synthesis of novel bioactive molecules.
Application
- Pharmaceutical Intermediate: A critical building block for the synthesis of advanced prostaglandin analogs and related therapeutic agents.
- Biochemical Research: Used as a reference standard and probe in studies of eicosanoid signaling pathways, inflammation, and smooth muscle physiology.
- Reference Material: Serves as a high-purity certified reference standard (CRS) for analytical method development and quality control in pharmaceutical manufacturing.
- Drug Discovery: A valuable starting material for medicinal chemistry programs targeting prostaglandin receptors (e.g., EP, FP, DP receptors).
- Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the biological effects of specific prostaglandin metabolites.
Basic Information
| Product Name | 9Alpha-11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Oic Acid, 1-Glyceryl Ester |
| CAS No. | 43042-79-1 |
| Molecular Formula | C23H38O7 |
| Molecular Weight | 426.55 g/mol |
| Synonyms | PGH2 Glyceryl Ester; 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid 1-glyceryl ester; Prostaglandin H2 1-Glyceryl Ester; 1-Glyceryl ester of 9,11,15-Trihydroxyprosta-5,13-dienoic acid; 9,11,15-Trihydroxyprosta-5,13-dienoic acid glyceryl ester; Glyceryl Prostaglandin H2; PGH2-G |
| EINECS | Contact for details |
Quality Control
Our 9Alpha-11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Oic Acid, 1-Glyceryl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate at -80°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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