Description

Dansyl-L-Leucine Cyclohexylammonium Salt is a high-purity, fluorescently labeled amino acid derivative used as a critical reagent in advanced biochemical research and analysis. Its core value lies in providing a sensitive and specific tag for the detection and quantification of peptides and proteins, particularly in chromatographic and electrophoretic techniques. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable, high-performance standards for method development and validation.

Application

• High-Performance Liquid Chromatography (HPLC) Standard: Used as a reference standard for calibrating systems and validating methods for amino acid and peptide analysis.
• Fluorescence Detection in Analytical Chemistry: Serves as a derivatizing agent to enhance the sensitivity and selectivity of detection for leucine and other amino acids.
• Biochemical Research & Proteomics: Employed in peptide sequencing, protein labeling studies, and investigating enzyme kinetics and mechanisms.
• Pharmaceutical Quality Control (QC): Acts as a critical component in assay development and impurity profiling for peptide-based drug substances.
• Capillary Electrophoresis (CE): Utilized as a fluorescent marker or internal standard in separation techniques for biomolecules.
• Synthesis of Fluorescent Probes: Functions as a building block for creating specialized diagnostic tools and sensors.

Basic Information

Product Name	Dansyl-L-Leucine Cyclohexylammonium Salt
CAS No.	42954-58-5
Molecular Formula	C24H39N3O4S
Molecular Weight	465.65 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-L-leucine cyclohexylammonium salt; DNS-Leu·CHA; Nε-Dansyl-L-leucine cyclohexylamine salt; L-Leucine, N-[5-(dimethylamino)-1-naphthalenesulfonyl]-, compd. with cyclohexanamine (1:1); Dansyl leucine cyclohexylammonium salt; N-Dansyl-L-leucine cyclohexylammonium salt
EINECS	Contact for details

Quality Control

Our Dansyl-L-Leucine Cyclohexylammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.