Description

Pyridine-3-Sulfonyl Chloride Hydrochloride is a key sulfonylating reagent and versatile synthetic intermediate. This compound is particularly valuable for introducing the pyridine-3-sulfonyl moiety into target molecules, enabling the synthesis of sulfonamides and other functionalized derivatives. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pyridine-sulfonyl group confers specific biological activity.
• Organic Synthesis Reagent: Functions as a robust sulfonylating agent for amines, alcohols, and other nucleophiles in complex molecule construction.
• Material Science Research: Employed in the creation of functional polymers, ligands, and metal-organic frameworks (MOFs) with tailored properties.
• Bioconjugation Chemistry: Useful for modifying biomolecules, peptides, and proteins to introduce sulfonate groups for solubility or labeling purposes.

Basic Information

Product Name	Pyridine-3-Sulfonyl Chloride Hydrochloride
CAS No.	42899-76-3
Molecular Formula	C5H5Cl2NO2S
Molecular Weight	214.07 g/mol
Synonyms	3-Pyridinesulfonyl Chloride Hydrochloride; Nicotinic Sulfonyl Chloride Hydrochloride; Pyridine-3-sulfonic acid chloride hydrochloride; 3-Pyridylsulfonyl Chloride Hydrochloride; 3-Sulfonylchloridopyridine Hydrochloride; Pyridine-3-SO2Cl·HCl
EINECS	Contact for details

Quality Control

Our Pyridine-3-Sulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.