Description

6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinoline is a fluorinated tetrahydroquinoline derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is crucial for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and quinoline structure can enhance biological activity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological processes and enzyme functions.
• Catalyst Ligand Development: Acts as a precursor for synthesizing novel chiral ligands used in asymmetric catalysis for producing enantiomerically pure compounds.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including novel fluorination and cyclization reactions.

Basic Information

Product Name	6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinoline
CAS No.	42835-89-2
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	2-Methyl-6-fluoro-1,2,3,4-tetrahydroquinoline; 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-fluoro-2-methylquinoline; 6-Fluoro-2-methyl-3,4-dihydro-1H-quinoline; Fluorinated tetrahydroquinoline derivative; FTHQ building block; 42835-89-2
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.