Description

(1S,4As,5R,8As)-5-[(E)-3-Methyl-4-Carboxy-3-Butenyl]-1,4A-Dimethyl-6-Methylenedecalin-1-Carboxylic Acid is a high-purity, structurally complex diterpenoid carboxylic acid of significant interest in advanced organic synthesis. Its unique decalin core and functionalized side chain make it a valuable chiral building block for the development of novel bioactive compounds. This intermediate is primarily sought by pharmaceutical research and fine chemical synthesis laboratories for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly in steroid-mimetic or terpenoid-based therapeutic research.
• Medicinal Chemistry Research: Used as a complex scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities with potential biological activity.
• Fine Chemical Synthesis: Employed as a sophisticated building block in multi-step organic syntheses requiring a rigid, polycyclic framework with defined stereochemistry.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling of related compounds.
• Biochemical Research: Investigated for its potential interactions with biological systems, given its structural similarity to natural diterpenoids.

Basic Information

Product Name	(1S,4As,5R,8As)-5-[(E)-3-Methyl-4-Carboxy-3-Butenyl]-1,4A-Dimethyl-6-Methylenedecalin-1-Carboxylic Acid
CAS No.	41988-89-0
Molecular Formula	C₂₀H₃₀O₄
Molecular Weight	334.45 g/mol
Synonyms	5-[(1E)-3-Methyl-4-carboxy-3-buten-1-yl]-1,4a-dimethyl-6-methylenedecahydro-1-naphthalenecarboxylic Acid; (E)-5-(3-Methyl-4-carboxybut-3-en-1-yl)-1,4a-dimethyl-6-methylenedecalin-1-carboxylic Acid; 41988-89-0; Diterpenoid Carboxylic Acid Derivative; Abietic Acid Derivative; Rosin Acid Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Identity and purity are confirmed via advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.