Description

3-(4-Trifluoromethylphenyl)Propenal is a versatile fluorinated aromatic aldehyde building block, characterized by its reactive propenal (acrolein) moiety attached to a trifluoromethylphenyl group. This compound is valued for its role in introducing both the trifluoromethyl group and an α,β-unsaturated carbonyl system into target molecules, enabling the synthesis of complex intermediates. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis Building Block: Employed in Michael additions, Diels-Alder reactions, and cyclocondensations to construct complex heterocyclic and polyfunctional compounds.

Basic Information

Item	Details
Product Name	3-(4-Trifluoromethylphenyl)Propenal
CAS No.	41917-83-3
Molecular Formula	C10H7F3O
Molecular Weight	200.16 g/mol
Synonyms	4-(Trifluoromethyl)cinnamaldehyde; (E)-3-[4-(Trifluoromethyl)phenyl]prop-2-enal; 3-(4-Trifluoromethylphenyl)-2-propenal; α,β-Unsaturated aldehyde derivative; Trifluoromethyl cinnamaldehyde; 4-Trifluoromethylcinnamaldehyde; 2-Propenal, 3-[4-(trifluoromethyl)phenyl]-; (E)-3-(4-(Trifluoromethyl)phenyl)acrylaldehyde
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethylphenyl)Propenal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.