Description

3,4,5,6-Tetrafluoropicolinonitrile is a high-value fluorinated heterocyclic building block, a key intermediate in advanced organic synthesis. Its unique structure, featuring a fully fluorinated pyridine ring and a reactive nitrile group, makes it indispensable for introducing tetrafluoropyridine motifs into complex molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used to construct advanced fluorinated pyridine-based herbicides, fungicides, and insecticides for improved efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized fluorinated ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, liquid crystals, and specialty polymers where fluorination alters electronic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic and mechanistic studies.

Basic Information

Product Name	3,4,5,6-Tetrafluoropicolinonitrile
CAS No.	41793-83-3
Molecular Formula	C6HF4N2
Molecular Weight	168.08 g/mol
Synonyms	2-Cyano-3,4,5,6-tetrafluoropyridine; Tetrafluoropicolinonitrile; 3,4,5,6-Tetrafluoro-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 3,4,5,6-tetrafluoro-; Picolinonitrile, 3,4,5,6-tetrafluoro-
EINECS	Contact for details

Quality Control

Our 3,4,5,6-Tetrafluoropicolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We support custom synthesis and can tailor specifications, including purity grades (e.g., >98%, >99%), to meet specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Handle and store in accordance with good laboratory/industrial practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.