Description

Indicine-n-Oxide is a pyrrolizidine alkaloid derivative with significant research and pharmaceutical interest. This compound matters as a key intermediate in the development of chemotherapeutic agents and for its role in biochemical research related to hepatotoxicity and metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of specialized chemotherapeutic compounds and targeted drug candidates.
• Biochemical Research: Used as a reference standard and active agent in studies investigating pyrrolizidine alkaloid toxicity, liver metabolism, and DNA alkylation mechanisms.
• Anticancer Agent Development: Serves as a model compound for researching and developing prodrugs and novel oncology treatments.
• Metabolite Studies: Employed in analytical and pharmacological research to study the biotransformation and pharmacokinetics of related alkaloids.
• Fine Chemical Synthesis: Utilized as a building block in the multi-step synthesis of complex natural product analogs and specialized organic molecules.
• Toxicology Reference Material: Acts as a certified standard in toxicological assays and safety evaluations for herbal products and dietary supplements.

Basic Information

Product Name	Indicine-n-Oxide
CAS No.	41708-76-3
Molecular Formula	C15H25NO6
Molecular Weight	315.36 g/mol
Synonyms	Indicine N-Oxide; Indicine-N-Oxide; NSC-132319; 1,2,3,5,6,7-Hexahydro-8-hydroxy-7-(hydroxymethyl)-8-methoxy-3-methyl-6,8-dioxopyrrolizine-4-carboxylic acid methyl ester N-oxide; (1R,7aR)-1-(Hydroxymethyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl 3-carboxy-2,2-dimethylpropanoate N-oxide; Pyrrolizidine alkaloid N-oxide
EINECS	Contact for details

Quality Control

Our Indicine-n-Oxide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, impurities, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.