Description

16,16-Dimethyl Prostaglandin A1 is a synthetic analog of prostaglandin A1, a potent bioactive lipid mediator. This modified compound offers enhanced metabolic stability and distinct biological activity profiles compared to its natural counterpart, making it a valuable research tool. It is primarily utilized in biochemical and pharmacological research to study cellular signaling pathways, inflammation, and vascular biology.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of eicosanoid signaling, receptor binding, and enzyme inhibition.
• Pharmacological Studies: Investigated for its effects on smooth muscle contraction, blood pressure regulation, and inflammatory responses in preclinical models.
• Cell Biology: Employed to explore its role in apoptosis (programmed cell death), cell proliferation, and differentiation mechanisms.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel therapeutic agents targeting prostaglandin pathways.
• Academic & Institutional Research: Essential for universities and research institutes focusing on lipidomics, metabolic disorders, and cardiovascular disease.

Basic Information

Product Name	16,16-Dimethyl Prostaglandin A1
CAS No.	41692-24-4
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl PGA1; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4,4-dimethyl-1-octen-1-yl]cyclopentyl]-5-heptenoic Acid; 16,16-Dimethylprostaglandin A1; DM-PGA1; PGA1 dimethyl analog
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl Prostaglandin A1 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.