Description

16,16-Dimethyl Prostaglandin E1 is a synthetic analog of prostaglandin E1, designed for enhanced metabolic stability and targeted biological activity. This compound is significant for its potent vasodilatory and antiplatelet properties, making it a valuable research tool and potential therapeutic agent. It is primarily needed by pharmaceutical R&D teams, academic researchers, and manufacturers of fine chemicals focused on cardiovascular, inflammatory, and cytoprotective applications.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics targeting vascular diseases and inflammation.
• Biochemical Research: Serves as a critical tool for studying prostaglandin receptors (EP receptors), signal transduction pathways, and cellular mechanisms related to vasodilation and cytoprotection.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and compound identification via HPLC, LC-MS, or NMR.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex prostaglandin analogs and specialized bioactive molecules.

Basic Information

Product Name	16,16-Dimethyl Prostaglandin E1
CAS No.	41692-15-3
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl PGE1; 16,16-Dimethylprostaglandin E1; 11α,15α-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid; 16,16-Dimethyl Prostaglandin E1; 16,16-Dim-PGE1; DM-PGE1; 16,16-Dimethylprosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-; (5Z,13E)-(9S,11R,15S)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl Prostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. For long-term storage, desiccate to minimize exposure to moisture. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.