Description

16,16-Dimethyl Prostaglandin A2 is a synthetic analog of prostaglandin A2, a potent bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and specific biological activity compared to its parent molecule. It serves as a critical research tool and intermediate in the pharmaceutical and life sciences sectors, particularly for investigating cellular signaling pathways and developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active intermediate in the synthesis of novel drug candidates targeting inflammation, cardiovascular function, and cellular proliferation.
• Biochemical Research: A key reagent for studying prostaglandin receptors, signal transduction mechanisms, and the role of eicosanoids in physiological and pathological processes.
• Cell Biology Studies: Employed to investigate apoptosis (programmed cell death), cell cycle regulation, and cellular stress responses in various in vitro models.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in pharmacology, biochemistry, and molecular biology.
• Pre-clinical Development: Utilized in animal studies to evaluate the pharmacokinetics, efficacy, and safety profiles of prostaglandin-based therapies.

Basic Information

Product Name	16,16-Dimethyl Prostaglandin A2
CAS No.	41691-92-3
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl PGA2; (5Z,13E)-(9S,11R,15R)-9,11,15-Trihydroxy-16,16-dimethyl-5,13-prostadienoic Acid; 16,16-Dimethylprostaglandin A2; DM-PGA2; PGA2 dimethyl analog; 16,16-Dimethyl-prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-; Prostaglandin A2, 16,16-dimethyl-
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl Prostaglandin A2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.