Description

(15S)-Latanoprost Acid CAS NO 41639-84-3 is a high-purity, synthetic prostaglandin F2α analog carboxylic acid, serving as the key active pharmaceutical ingredient (API) intermediate for the synthesis of latanoprost. This compound is critically important for its role in the production of ophthalmic solutions used to treat glaucoma and ocular hypertension by reducing intraocular pressure. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the development and production of advanced ophthalmic medications.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary intermediate in the commercial manufacturing of Latanoprost, a frontline glaucoma medication.
• Ophthalmic Drug Development: Critical raw material for R&D into novel prostaglandin-based treatments for ocular conditions.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Pharmaceutical Intermediates: Serves as a building block for synthesizing related prostaglandin analogs and derivatives.
• Biochemical Research: Tool compound for studying FP receptor activity and prostaglandin signaling pathways in preclinical research.

Basic Information

Product Name	(15S)-Latanoprost Acid
CAS No.	41639-84-3
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	(15S)-Latanoprost; Latanoprost Impurity A; Latanoprost Acid; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid; 13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2α; Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate (Latanoprost) related compound A; Prostaglandin F2α analog carboxylic acid.
EINECS	Contact for details

Quality Control

Our (15S)-Latanoprost Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical intermediates. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for API starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in original packaging and desiccated if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.