Description

7-Bromo-2,1,3-Benzothiadiazole-4-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate primarily used in the synthesis of advanced materials and active pharmaceutical ingredients. Its core value lies in the reactive sulfonyl chloride and bromo-substituted benzothiadiazole moieties, which enable precise molecular construction for demanding applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require a reliable, high-purity building block for complex heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the benzothiadiazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for enhanced biological activity and selectivity.
• Functional Material Precursor: Serves as a building block for organic semiconductors, fluorescent dyes, and sensors due to the electron-accepting properties of the benzothiadiazole unit.
• Polymer Modification: Employed to introduce sulfonamide or other functional groups into polymer chains to alter physical properties like solubility, thermal stability, or conductivity.
• Cross-coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille), allowing for further structural diversification.
• Ligand and Catalyst Development: Used to create complexing agents or ligands for catalysis, where the sulfonyl chloride group facilitates attachment to various supports or frameworks.

Basic Information

Product Name	7-Bromo-2,1,3-Benzothiadiazole-4-Sulfonyl Chloride
CAS No.	41512-06-5
Molecular Formula	C6H2BrClN2O2S2
Molecular Weight	313.58 g/mol
Synonyms	4-Bromo-7-chlorosulfonyl-2,1,3-benzothiadiazole; 7-Bromo-2,1,3-benzothiadiazole-4-sulfonyl chloride; 2,1,3-Benzothiadiazole-4-sulfonyl chloride, 7-bromo-; 4-Bromo-2,1,3-benzothiadiazole-7-sulfonyl chloride; BTB-Sulfonyl Chloride; 7-Bromo-BTD-SO2Cl
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,1,3-Benzothiadiazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.