Description

Methanesulfonyl Bromide is a versatile and highly reactive organosulfur reagent, primarily used as a brominating and sulfonylating agent in organic synthesis. Its value lies in its ability to introduce the methanesulfonyl (mesyl) group or act as a source of electrophilic bromine, facilitating key transformations in complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for active pharmaceutical ingredients (APIs), intermediates, and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the preparation of sulfonamides, sulfonate esters, and other bioactive molecules used in drug discovery and development.
• Agrochemical Production: Employed in the synthesis of herbicides, fungicides, and insecticides that require sulfonyl or bromo functional groups.
• Peptide Chemistry: Used as a coupling agent or for the protection/deprotection of functional groups during peptide synthesis.
• Polymer Modification: Acts as a functionalization agent to introduce bromo or mesyl groups into polymer chains, altering their physical and chemical properties.
• Organic Synthesis Reagent: Facilitates various reactions including bromination, alkylation, and as a precursor for other sulfonyl halides.
• Chemical Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	Methanesulfonyl Bromide
CAS No.	41138-92-5
Molecular Formula	CH3BrO2S
Molecular Weight	158.99 g/mol
Synonyms	Methanesulfonic Acid Bromide; Mesyl Bromide; Methylsulfonyl Bromide; Bromomethanesulfonyl; Methanesulfonylbromide; Methanesulphonic acid bromide; Bromo(methyl)sulfone
EINECS	Contact for details

Quality Control

Our Methanesulfonyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required by pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.