Description

1-(2-Chloroethyl)-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a reactive chloroethyl side chain and a fluorinated aromatic ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated phenyl moiety linked via an ethyl spacer.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & Electronic Chemicals: Serves as a building block for fluorinated liquid crystal materials and other specialty electronic chemicals.
• Organic Synthesis & Research: A valuable reagent for introducing the 2-(4-fluorophenyl)ethyl group into target molecules via nucleophilic substitution or cross-coupling reactions.
• Material Science: Intermediate in the production of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	1-(2-Chloroethyl)-4-Fluorobenzene
CAS No.	41037-51-8
Molecular Formula	C8H8ClF
Molecular Weight	158.60 g/mol
Synonyms	2-(4-Fluorophenyl)ethyl chloride; 4-Fluorophenethyl chloride; 1-Chloro-2-(4-fluorophenyl)ethane; (4-Fluorophenyl)ethyl chloride; 2-Chloro-1-(4-fluorophenyl)ethane; 4-Fluorobenzenechloroethane; β-Chloro-4-fluoroethylbenzene; p-Fluorophenethyl chloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-4-Fluorobenzene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.