Description

Perhydrohistrionicotoxin is a saturated derivative of the potent neurotoxin histrionicotoxin, representing a key structural analog for advanced research. This compound is of significant interest in neuroscience and pharmacology for its utility as a biochemical tool to study nicotinic acetylcholine receptors (nAChRs) and ion channel function. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialized chemical manufacturers focused on neuroactive compounds and receptor ligand development.

Application

• Neuroscience Research: A critical biochemical probe for investigating the structure, function, and modulation of nicotinic acetylcholine receptors (nAChRs).
• Pharmacological Studies: Used in the development and screening of novel therapeutics targeting neurological disorders and channelopathies.
• Toxicology & Mechanism of Action: Serves as a reference standard and tool for studying the effects of neurotoxins and their derivatives on synaptic transmission.
• Chemical Synthesis: An important intermediate or reference compound in the synthesis of specialized neuroactive molecules and labeled analogs for tracer studies.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in neurochemistry and molecular biology.

Basic Information

Product Name	Perhydrohistrionicotoxin
CAS No.	40709-29-3
Molecular Formula	C19H35NO
Molecular Weight	293.49 g/mol
Synonyms	Perhydrohistrionicotoxin; Dihydrohistrionicotoxin (fully saturated); 1-Azaspiro[5.5]undecan-8-ol, 2-butyl-2-ethyl-7-methyl-; Histrionicotoxin, perhydro-; HTX analog; nAChR non-competitive antagonist
EINECS	Contact for details

Quality Control

Our Perhydrohistrionicotoxin is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research integrity and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.