Description

1-Octanesulphonyl Fluoride is a specialized organosulfur compound featuring a long-chain alkyl group and a highly reactive sulfonyl fluoride moiety. This unique structure makes it a valuable reagent in modern synthetic chemistry, particularly for the selective introduction of the octanesulfonyl group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as sulfonylation reactions and as a building block for more complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the octanesulfonyl group can influence bioavailability and activity.
• Chemical Biology Probe: Serves as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent inhibitors targeting specific enzymes.
• Polymer & Material Science: Employed as a monomer or modifier in the creation of specialty polymers, surfactants, and materials with specific surface properties.
• Sulfonylation Reagent: Facilitates the introduction of the octanesulfonyl protecting group or functionality onto alcohols, amines, and other nucleophiles in complex molecule synthesis.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	1-Octanesulphonyl Fluoride
CAS No.	40630-63-5
Molecular Formula	C₈H₁₇FO₂S
Molecular Weight	196.28 g/mol
Synonyms	Octane-1-sulfonyl fluoride; 1-Octanesulfonyl fluoride; n-Octanesulfonyl fluoride; Octylsulfonyl fluoride; Perfluorooctanesulfonyl fluoride (historical context, not accurate for this hydrogen-containing compound); 40630-63-5; NSC 401119
EINECS	Contact for details

Quality Control

Our 1-Octanesulphonyl Fluoride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.