Description

1-[3-(Trifluoromethyl)Phenyl]Tricyclo[3.3.1.13,7]Decan-2-Ol is a high-value, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining the rigid, lipophilic adamantane cage with a trifluoromethylphenyl group, offers exceptional potential for modulating the physical and biological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the adamantane core contributes to weather resistance and systemic activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent for developing high-performance polymers with specific thermal and chemical resistance properties.
• Ligand & Catalyst Development: The sterically demanding structure is valuable for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Fluorine Chemistry Building Block: Exploited in medicinal chemistry for its trifluoromethyl group, which is known to improve membrane permeability and metabolic stability.
• Life Science Research: Utilized as a biochemical tool or probe in academic and industrial research to study enzyme interactions and cellular processes.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Tricyclo[3.3.1.13,7]Decan-2-Ol
CAS No.	40571-18-4
Molecular Formula	C₁₇H₁₉F₃O
Molecular Weight	296.33 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]adamantan-2-ol; 2-Adamantanol, 1-[3-(trifluoromethyl)phenyl]-; 1-(3-Trifluoromethylphenyl)-2-adamantanol; 1-(3-(Trifluoromethyl)phenyl)tricyclo[3.3.1.1³,⁷]decan-2-ol; 1-(m-Trifluoromethylphenyl)-2-hydroxyadamantane; 40571-18-4; Adamantane derivative CAS 40571-18-4
EINECS	Contact for details

Quality Control

Our production of 1-[3-(Trifluoromethyl)Phenyl]Tricyclo[3.3.1.13,7]Decan-2-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, making this product suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.