Description

(22E)-6α,7α-Epoxy-5-Hydroxy-D(17A)-Homo-18,26,27-Trinor-5α-Cholesta-2,13,15,17,22-Pentene-1,24-Dione is a high-purity, complex steroidal derivative with a unique pentene-dione structure. This compound is a critical advanced pharmaceutical intermediate (API) for the research and synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in academic and industrial research exploring steroidal pathways and receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with potential biological activity.
• Process Development: Supports process chemistry and scale-up studies for the production of specialized steroidal compounds.

Basic Information

Product Name	(22E)-6α,7α-Epoxy-5-Hydroxy-D(17A)-Homo-18,26,27-Trinor-5α-Cholesta-2,13,15,17,22-Pentene-1,24-Dione
CAS No.	40071-62-3
Molecular Formula	C₂₇H₃₄O₅
Molecular Weight	438.56 g/mol
Synonyms	6α,7α-Epoxy-5-hydroxy-D-homo-18,26,27-trinor-5α-cholesta-2,13,15,17,22-pentaene-1,24-dione; (22E)-6α,7α-Epoxy-5-hydroxy-D-homo-18,26,27-trinor-5α-cholesta-2,13,15,17,22-pentaene-1,24-dione; Steroidal Epoxide Dione; 40071-62-3; D-Homo Steroid Derivative; Pentene Dione Steroid Intermediate
EINECS	Contact for details

Quality Control

Our (22E)-6α,7α-Epoxy-5-Hydroxy-D(17A)-Homo-18,26,27-Trinor-5α-Cholesta-2,13,15,17,22-Pentene-1,24-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and spectroscopic methods, to ensure high purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.