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1,2-o-Isopropylidene-β-L-Idofuranuronic-6-13C Acid γ-Lactone CAS NO 40010-58-0


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CAS No.:40010-58-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-o-Isopropylidene-β-L-Idofuranuronic-6-13C Acid γ-Lactone is a high-purity, carbon-13 (13C) labeled derivative of a key carbohydrate intermediate. This compound is specifically engineered for advanced research and development, providing a critical isotopic tracer for metabolic and synthetic pathway studies. It is an essential building block for pharmaceutical chemists and life science researchers working on nucleoside analogs, carbohydrate-based drugs, and sophisticated biochemical probes.

Application

  • Isotopic Tracer in Metabolic Studies: Utilized as a 13C-labeled precursor in NMR and mass spectrometry-based research to track metabolic pathways and enzyme mechanisms.
  • Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
  • Glycochemistry Research: Acts as a protected and labeled starting material for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
  • Biochemical Probe Development: Used to create labeled probes for studying carbohydrate-processing enzymes, transporters, and receptors.
  • Reference Standard: Employed as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name 1,2-o-Isopropylidene-β-L-Idofuranuronic-6-13C Acid γ-Lactone
CAS No. 40010-58-0
Molecular Formula C9H1213CO6
Molecular Weight ~217.18 g/mol (for 13C6 labeled form)
Synonyms 1,2-O-Isopropylidene-β-L-idofuranuronic acid-6-13C γ-lactone; (3aR,5R,6S,6aR)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-6-carboxylic-6-13C acid γ-lactone; 6-13C-L-Idono-1,4-lactone 2,3:5,6-di-O-isopropylidene; 13C6-Labeled L-Idono-1,4-lactone diacetonide; 1,2:5,6-Di-O-isopropylidene-α-L-idofuranurono-6-13C-6,3-lactone; Isotopically labeled carbohydrate lactone.
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Quality Control

This high-value 13C-labeled compound is produced and handled under strict quality protocols to ensure isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic methods. Our quality systems are designed to meet the exacting standards of pharmaceutical R&D and analytical reference material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be kept under inert conditions if long-term stability is required. Handle and store in accordance with good laboratory practices.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure (1H & 13C)
Purity (HPLC) ≥ 98.0%
Isotopic Enrichment ≥ 99 atom % 13C at C-6
Specific Rotation Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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