Description

2-Fluoropyrazine 98 is a high-purity fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom into the pyrazine scaffold, enabling precise modulation of electronic properties, metabolic stability, and lipophilicity in target molecules. This reagent is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for constructing specialized nitrogen-containing ligands used in homogeneous catalysis and material science.
• Functional Material Synthesis: Employed in the development of electronic materials, such as organic semiconductors and liquid crystals, due to its electron-deficient aromatic system.
• Fluorine Chemistry Library Building: A valuable starting material for generating diverse compound libraries in medicinal chemistry for high-throughput screening (HTS).

Basic Information

Product Name	2-Fluoropyrazine 98
CAS No.	4949-13-7
Molecular Formula	C4H3FN2
Molecular Weight	98.08 g/mol
Synonyms	2-Fluoropyrazine; Fluoropyrazine; Pyrazine, 2-fluoro-; 2-Fluoro-1,4-diazine; 2-Fluoropyrazine (98%); 2-FPZ; 4949-13-7
EINECS	225-588-4

Quality Control

Our 2-Fluoropyrazine 98 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to confirm identity and assay. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, impurity profile, and physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.