Description

Glycerol Impurity (Disulfide Oxidation Product) CAS NO 4807-52-7 is a high-purity chemical reference standard used for the identification and quantification of process-related impurities in glycerol and related chemical streams. This compound is critical for ensuring product quality and safety in industries where glycerol purity is paramount. It is primarily utilized by analytical laboratories, quality control departments, and research & development teams within the pharmaceutical, fine chemical, and personal care sectors for method development and validation.

Application

• Pharmaceutical Impurity Profiling: Serves as a certified reference material (CRM) for HPLC, GC, or LC-MS analysis to monitor and control impurities in glycerol used as an excipient or solvent in drug formulations.
• Quality Control & Assurance: Essential for establishing specification limits and testing methods for glycerol batches in manufacturing, ensuring compliance with pharmacopeial standards (USP/EP).
• Method Development and Validation: Used by analytical chemists to develop, optimize, and validate chromatographic methods for the specific detection of disulfide-based oxidation products.
• Research on Degradation Pathways: Aids in stability studies and research to understand the oxidation mechanisms and degradation pathways of glycerol under various storage and processing conditions.
• Fine Chemical Synthesis: Acts as a marker or standard in the purification and analysis of glycerol-derived chemicals, ensuring the removal of specific oxidation by-products.

Basic Information

Product Name	Glycerol Impurity (Disulfide Oxidation Product)
CAS No.	4807-52-7
Molecular Formula	C6H14O8S2
Molecular Weight	278.30 g/mol
Synonyms	1,3-Di-O-(2,3-dihydroxypropyl) 2,2'-dithiodiglycerol; Bis(2,3-dihydroxypropyl) disulfide; Glycerol disulfide; Dithiodiglycerol; 2,2'-Dithiobis(1,3-propanediol) derivative; Oxidation product of glycerol; Thioglycerol dimer
EINECS	Contact for details

Quality Control

This analytical standard is manufactured under strict quality control conditions to ensure high purity and batch-to-batch consistency, suitable for use in regulated environments. Identity and purity are confirmed via advanced spectroscopic and chromatographic techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing the analytical results, test methods, and traceability information.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.