Description

4-Bromo-3-Nitrobenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group acts as an excellent electrophile for sulfonamide formation and the bromo-nitro substituted aromatic ring provides sites for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), specialty dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including protease inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides by serving as a scaffold for active molecule development.
• Functional Material Production: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex azo dyes and pigments due to its nitro and bromo substituents.
• Chemical Biology Research: Employed as a labeling or bioconjugation reagent for probing protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom organic synthesis and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-3-Nitrobenzene-1-Sulfonyl Chloride
CAS No.	4750-22-5
Molecular Formula	C6H3BrClNO4S
Molecular Weight	300.51 g/mol
Synonyms	4-Bromo-3-nitrobenzenesulfonyl chloride; 3-Nitro-4-bromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-3-nitro-; 1-Bromo-2-nitro-4-(chlorosulfonyl)benzene; NSC 403119; 4750-22-5; 4-Bromo-3-nitrobenzene-1-sulphonyl chloride; 4-Bromo-3-nitrobenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Nitrobenzene-1-Sulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and titration to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP and ISO 9001 standards for regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.