Description

St-91 CAS NO 4749-61-5 is a specialized chemical compound, also known as 2,4,6-Triisopropylbenzenesulfonyl chloride, which serves as a key reagent in organic synthesis. Its primary value lies in its role as a highly effective sulfonylation agent and protecting group, particularly for amines and alcohols in the synthesis of complex molecules. This product is essential for research and development laboratories, pharmaceutical intermediates manufacturing, and fine chemical production where precise molecular modification is required.

Application

• Pharmaceutical Intermediate Synthesis: Used as a sulfonylating agent in the production of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Employed as a protecting group for amino acids during solid-phase and solution-phase peptide synthesis.
• Agrochemical Manufacturing: A key reagent in the synthesis of certain herbicides, fungicides, and other crop protection agents.
• Material Science Research: Utilized in the modification of polymer surfaces and the creation of novel organic materials.
• Dye and Pigment Production: Acts as an intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Academic & Industrial R&D: A valuable tool for chemists in exploratory synthesis and process development across various chemical sectors.

Basic Information

Product Name	St-91
CAS No.	4749-61-5
Molecular Formula	C15H23ClO2S
Molecular Weight	302.86 g/mol
Synonyms	2,4,6-Triisopropylbenzenesulfonyl chloride; TIPS-Cl; 2,4,6-Triisopropylphenylsulfonyl chloride; Trisopropylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 2,4,6-tris(1-methylethyl)-; TPS-Cl; St-91 Reagent; Sulfonylating Agent St-91
EINECS	225-257-5

Quality Control

Every batch of St-91 is manufactured and tested under a strict quality management system to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing, including purity assay and impurity profiling, to meet the high standards required by the pharmaceutical and fine chemical industries. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.