Description

Bromoacetic Acid, [1-14C] CAS NO 4561-21-1 is a carbon-14 labeled isotopologue of bromoacetic acid, a key alkylating agent and synthetic intermediate. This radiolabeled compound is essential for precise metabolic and pharmacokinetic studies, enabling researchers to track molecular pathways with high specificity. It is primarily used by pharmaceutical R&D teams, agrochemical scientists, and academic researchers in the development and analysis of novel compounds.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to elucidate the absorption, distribution, metabolism, and excretion (ADME) profiles of new chemical entities.
• Agrochemical Research: Employed in environmental fate studies to track the degradation pathways and metabolite formation of pesticides and herbicides.
• Biochemical Pathway Analysis: Serves as a labeled precursor for synthesizing other 14C-labeled intermediates to study specific enzymatic reactions and biosynthetic routes.
• Organic Synthesis Intermediate: Acts as a radiolabeled building block for the preparation of more complex molecules where carbon-14 tracing is required.
• Regulatory Compliance Testing: Supports studies required for regulatory submissions to agencies like the FDA and EPA, providing crucial data on compound fate.

Basic Information

Product Name	Bromoacetic Acid, [1-14C]
CAS No.	4561-21-1
Molecular Formula	C14CH2BrCOOH
Molecular Weight	138.96 (for unlabeled); Contact for specific activity of labeled product
Synonyms	2-Bromo[1-14C]acetic Acid; [1-14C]Bromoacetic Acid; Carboxy-14C Bromoacetic Acid; Bromoethanoic Acid-1-14C; Monobromo[1-14C]acetic Acid; NSC 81624-14C; BAA-14C
EINECS	Contact for details

Quality Control

Every batch of Bromoacetic Acid, [1-14C] is produced and analyzed under strict quality systems to ensure traceability and reliability for critical research. Certificates of Analysis (COA) are provided, detailing key parameters such as radiochemical purity, specific activity, and chemical purity, typically determined by HPLC and radio-HPLC. Our quality commitment aligns with the standards expected for radiolabeled compounds in GLP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. This product is a strong acid/organic solvent and should be handled with appropriate precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Chemical Purity (HPLC)	≥ 95%
Solvent	Specified on COA (e.g., Toluene, Water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.