Description

4-Chloro-2-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its dual functional groups make it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, antibiotics, and protease inhibitors.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that require the sulfonyl moiety for biological activity.
• Dyestuff and Pigment Production: Acts as an intermediate for creating sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Chemistry: Employed as a modifying agent or cross-linking monomer to introduce sulfonyl chloride groups into polymer backbones for functional materials.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and synthesizing novel chemical entities in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	4-Chloro-2-Nitrobenzenesulfonyl Chloride
CAS No.	4533-96-4
Molecular Formula	C6H3Cl2NO4S
Molecular Weight	280.06 g/mol
Synonyms	2-Nitro-4-chlorobenzenesulfonyl chloride; 4-Chloro-2-nitrobenzenesulfonyl chloride; 4-Chloro-2-nitrobenzene-1-sulfonyl chloride; 1-Chloro-4-(chlorosulfonyl)-3-nitrobenzene; NSC 403107; Benzenesulfonyl chloride, 4-chloro-2-nitro-; p-Chloro-o-nitrobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Nitrobenzenesulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	89 - 93 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.