Description

Ethanol, [1-14C] CAS NO 4502-04-9 is a carbon-14 labeled isotopologue of ethanol, where the radioactive isotope 14C is specifically incorporated at the first carbon position. This compound is an essential tracer molecule for metabolic and biochemical research, enabling precise tracking of ethanol's fate in biological systems. It is primarily used by researchers in pharmaceutical development, environmental science, and metabolic studies who require high-specific-activity radiolabeled compounds for autoradiography, ADME studies, and pathway analysis.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of ethanol and related compounds in preclinical research.
• Biochemical Pathway Analysis: Employed to elucidate metabolic pathways, such as the ethanol oxidation pathway involving alcohol dehydrogenase and aldehyde dehydrogenase.
• Environmental Fate Studies: Tracks the biodegradation and environmental transformation of ethanol and its derivatives in soil and water systems.
• Autoradiography: Serves as a precursor for synthesizing other 14C-labeled compounds or is used directly in tissue distribution studies via autoradiographic techniques.
• Enzyme Mechanism Studies: Utilized to study the kinetics and mechanisms of enzymes that process ethanol or its metabolic intermediates.
• Quality Control Reference Standard: Acts as a certified reference material in analytical laboratories for calibrating equipment and validating methods for ethanol detection.

Basic Information

Product Name	Ethanol, [1-14C]
CAS No.	4502-04-9
Molecular Formula	C14CH3CH2OH / C2H6O (with 14C at C-1)
Molecular Weight	~46.07 g/mol (exact mass depends on 14C incorporation)
Synonyms	[1-14C]Ethanol; Ethanol-1-14C; 1-14C-Ethanol; Ethyl Alcohol-1-14C; [14C]Ethanol; Carbon-14 Labeled Ethanol; Radioactive Ethanol; 14C-EtOH; Ethanol (carbon-14 labeled)
EINECS	Contact for details

Quality Control

Every batch of Ethanol, [1-14C] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed data on radiochemical purity, chemical purity, specific activity, and solvent composition.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. Due to its highly volatile nature, ensure containers are securely sealed to prevent evaporation and potential exposure. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent	Ethanol or Water (as specified)
Concentration	1.0 mCi/mL (or as customized)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.