Description

3-Amino-Benzenesulfonyl Chloride is a key aromatic sulfonyl chloride derivative, serving as a versatile and reactive intermediate in advanced organic synthesis. Its primary value lies in its ability to introduce the sulfonamide functional group, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Core building block for the synthesis of sulfonamide-based drugs, including diuretics, anticonvulsants, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate sulfonamide moieties.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Modification: Employed to introduce sulfonamide groups into polymer chains, altering properties like hydrophilicity, adhesion, and ionic conductivity.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed coupling reactions to create complex biaryl structures for advanced applications.

Basic Information

Product Name	3-Amino-Benzenesulfonyl Chloride
CAS No.	4431-74-7
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	m-Aminobenzenesulfonyl Chloride; 3-Aminophenylsulfonyl Chloride; Metanilic Acid Chloride; Benzenesulfonyl chloride, 3-amino-; 3-Aminobenzene-1-sulfonyl chloride; Meta-Sulfanilyl Chloride; 3-Sulfanilyl Chloride
EINECS	224-624-6

Quality Control

Every batch of our 3-Amino-Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide full traceability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee consistent quality and performance for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, oxidizers, and sources of heat.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	138°C - 142°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.