Description

2-Phthalimidoethanesulfonyl Chloride is a specialized sulfonyl chloride derivative primarily used as a key synthetic intermediate in organic and medicinal chemistry. Its value lies in its reactive sulfonyl chloride group, which facilitates the introduction of the phthalimidoethanesulfonyl moiety into target molecules, enabling the synthesis of complex compounds. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the phthalimidoethanesulfonyl group confers specific biological activity.
• Peptide Modification & Bioconjugation: Serves as a reagent for selectively modifying amino groups on peptides or proteins, useful in creating bioconjugates or probes.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the production of specialty polymers with tailored properties like thermal stability or specific reactivity.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing sulfonyl groups in multi-step synthetic routes for complex organic molecules.
• Research & Development: A valuable tool in academic and industrial R&D laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Phthalimidoethanesulfonyl Chloride
CAS No.	4403-36-5
Molecular Formula	C10H8ClNO4S
Molecular Weight	273.69 g/mol
Synonyms	N-(2-Chlorosulfonylethyl)phthalimide; 2-(Phthalimido)ethanesulfonyl Chloride; 1-(2-Chloro-2-oxoethylsulfonyl)isoindoline-1,3-dione; Phthalimidoethanesulfonyl Chloride; 2-Phthalimidoethanesulphonyl Chloride; N-(2-Chloro-2-oxoethylsulfonyl)phthalimide; 2-(1,3-Dioxoisoindolin-2-yl)ethanesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Phthalimidoethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.