Description

Phenylthiohydantoin-Norleucine is a specialized amino acid derivative used in advanced biochemical research and synthesis. This compound is critical for applications requiring high-purity, structurally defined building blocks, such as peptide sequencing and the development of novel bioactive molecules. It serves the needs of research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in proteomics and custom peptide production.

Application

• Peptide Sequencing & Analysis: Used as a reference standard or derivatization agent in Edman degradation and related protein/peptide sequencing techniques.
• Pharmaceutical Research: Serves as a key intermediate or building block in the synthesis of novel peptide-based drug candidates and therapeutic agents.
• Proteomics & Biochemical Studies: Employed in the study of protein structure, function, and post-translational modifications.
• Custom Peptide Synthesis: Acts as a protected norleucine derivative for the solid-phase or solution-phase synthesis of specialized peptides.
• Analytical Standard: Utilized as a high-purity standard for method development and calibration in HPLC, LC-MS, and other chromatographic systems.
• Academic Research: A valuable tool in university and institutional labs for fundamental research in organic chemistry and biochemistry.

Basic Information

Product Name	Phenylthiohydantoin-Norleucine
CAS No.	4333-22-6
Molecular Formula	C13H16N2O2S
Molecular Weight	264.34 g/mol
Synonyms	PTH-Norleucine; 2-[(Phenylamino)thioxomethyl]amino]hexanoic Acid; Norleucine Phenylthiohydantoin; PTH-Nle; (RS)-2-[(Phenylcarbamothioyl)amino]hexanoic Acid; 5-(2-Aminobutyl)-2-thioxoimidazolidin-4-one (related structure); Edman Degradation Derivative of Norleucine
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin-Norleucine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.