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Ethynylmagnesium Bromide CAS NO 4301-14-8


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CAS No.:4301-14-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethynylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its core value lies in its ability to act as a powerful nucleophile for the efficient introduction of the ethynyl (acetylene) group into target molecules, enabling the construction of complex carbon frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise carbon-carbon bond formation for developing active ingredients and novel polymers.

Application

  • Pharmaceutical Intermediate Synthesis: Key building block for creating acetylene-containing active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Production: Used in the synthesis of herbicides, fungicides, and plant growth regulators that incorporate acetylene functionalities.
  • Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers and conductive materials.
  • Fine Chemical Manufacturing: Employed in the production of complex organic molecules, including flavors, fragrances, and dyes.
  • Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.
  • Liquid Crystal & OLED Material Synthesis: Used to create advanced organic electronic materials with specific optoelectronic properties.

Basic Information

Product Name Ethynylmagnesium Bromide
CAS No. 4301-14-8
Molecular Formula C2HBrMg
Molecular Weight 129.24 g/mol
Synonyms Magnesium, bromoethynyl-; Bromo(ethynyl)magnesium; Ethynylmagnesium bromide solution; Acetylenylmagnesium bromide; Ethynyl Grignard reagent; Bromomagnesioacetylene; (Bromoethynyl)magnesium
EINECS 224-339-9

Quality Control

Our Ethynylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as concentration, titration assay, and impurity profile. Our quality management system is designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area must be cool, dry, and well-ventilated, away from sources of ignition, moisture, and incompatible materials such as acids, water, and oxidizing agents.

Specification

Item Specification
Appearance (Solution) Clear, colorless to light brown
Concentration (in THF or Ether) 0.5 M, 1.0 M, or 2.0 M (Custom)
Assay (Titration) ≥ 95%
Identification (IR) Conforms
Water Content (Karl Fischer) ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.